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doi: 10.3389/fpsyt.2022.835993 144 SinclairDFeatherstoneRNaschekMNamJDuAWrightSet al

Intranasal delivery showed lower and more variable absorption between subjects

Available from: Clinical Trial Identifier: NCT03804268

Furthermore, in vivo experiments revealed that the long-term oral administration of L-citrulline offered protection against hyperglycemia-induced retinal vasodilator dysfunction by stimulates nitric oxide (NO) biosynthesis via the recycling of L-citrulline to L-arginine (Mori et al., 2015, 2021)