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doi: 10.1038/nrd1495 177 CiechomskaMRoszkowskiLMaslinskiW

Figure 11 The phosphinic group is, as compared to, e.g., thiols and hydroxamic acids more weakly binding to zinc ions in metalloproteases and a significantly improved selectivity could be achieved by systematic variations of the side chains at P1 and P2 positions of 43

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