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Fatty acids in cells can derive from exogenous resources or de novo fatty acid synthesis (Gaschler and Stockwell, 2017), especially phosphatidylethanolamine (PE)-containing phospholipids with arachidonic acid (AA) and adrenic acid (AdA)

Sadly, up to 1/3 of the population presently suffers from some form of chronic disease

Consequently, its potential to enhance immune recovery following T cell-depleting, total body irradiation-based hematopoietic stem cell transplantation is being explored when it is coadministered with leuprolide acetate (NCT01746849) (Table 2) or in combination with busulfan, melphalan, and fludarabine (NCT00629798)

doi: 10.1021/jacs.1c09525