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The iAs methylation requires the supply of the methyl group donor SAM and reduced glutathione (GSH) by the OCM pathway

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Expression of peptides, toxic proteins, and proteins from a single reading frame Intein technology can be used to express challenging targets: small peptides can be expressed as part of properly folded proteins with affinity domains, toxic proteins can be expressed in an inactivated format, and proteins that function in an essential stoichiometry can be expressed from a single open reading frame

The immune-enhancing protein is being studied for its potential in cancer treatment