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By utilizing H 2 O 2 we mimic the highly oxidative environment of intestinal inflammation and further our understanding of the macrophages response to this environment

Figure 3 5.1 Epigenetic regulatory mechanisms EED exposure fundamentally alters the epigenetic landscape through modifications to DNA methylation patterns, histone modifications, and non-coding RNA expression profiles, creating molecular changes that persist across generations and potentially affect offspring health in unprecedented ways

Besides, Z-VAD-FMK, an apoptosis inhibitor, scarcely rescued NSBSO-induced cell death in 4T1 cells (Additional file 1: Fig

We also perform laboratory tests to screen for pre-existing conditions like diabetes or hypothyroidism that could be contributing to weight gain