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Description

The amplification of GAA trinucleotides in the FRDA gene is closely related to the accumulation of iron in mitochondria

Ting et al

A deletion occurs when part of a chromosome is lost

Patients with PCOS presenting with hyperandrogenic manifestations such as hirsutism, acne and alopecia may benefit from anti-androgen therapies (e.g., spironolactone, flutamide, or finasteride) that inhibit androgen synthesis or receptor activity, thereby ameliorating cutaneous and pilosebaceous symptoms (Lizneva et al., 2016)