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Moreover, two studies performed on the p.A382T mutation [38, 39] have reported common bioenergetic features such as mitochondrial fragmentation, but also discrepancies in OCR values and mitochondrial ROS content

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10.1186/s12967-024-04942-0 25 DongR.TianJ.HuangZ.YuQ.XieJ.LiB.et al (2023)

234,235,236,237,238 This cascade of events can cause damage to renal capillary endothelial cells and contribute to the development of renal atherosclerosis