leukemia and glutathione Glutathione-Dependent Pathways in Cancer Cells Sgc8 aptamer targeted glutathione-responsive nanoassemblies

Sgc8 aptamer targeted glutathione responsive nanoassemblies containing Ara C prodrug for the treatment of acute lymphoblastic leukemia Nanoscale (RSC Publishing) Excited to share our #RedoxBiology @sciencedirect @SFRBM article showing that #epigenetic defect in #leukemia creates vulnerability for #ferroptosis upon the use of #glutathione inhibitors, work led by Lucas Pontel @LucPontel @CarrerasIJC https: t.co Targeting Aberrant Glutathione Metabolism to Eradicate Human Acute Myelogenous Leukemia Cells* Journal of Biological Chemistry Glutathione determines chronic myeloid leukemia vulnerability to an inhibitor of CMPK and TMPK Communications Biology

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