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In vitro studies have shown that PQQ-TME, an esterified form of PQQ, exhibits twice the BBB permeability of PQQ and demonstrates higher inhibitory activity against the fibrillation of -synuclein, A 1-42, and prion protein

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Yan H, Peng Z, Zhang H, Wang B, Xu W, He Z (2025) Cadmium minimization in crops: a trade-off with mineral nutrients in safe breeding