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1 Introduction Vitamin E is an essential micronutrient and a fat-soluble vitamin that acts as an antioxidant in the detoxification chain of fat-soluble to water-soluble toxic radicals

Enhanced immune function Glutathione strengthens immune responses by regulating inflammation and supporting immune cell function

Following the designated treatments, the rectal region was locally exposed to a single dose of 20 Gy X-ray irradiation, as determined in preliminary dose-selection experiments (see Supporting Information)

Picein, a natural compound derived from plants, suppresses ferroptotic responses after TBIincluding ferroptosis-related gene expression, iron overload, and lipid peroxidationand demonstrates greater efficacy than Fer-1 in restoring GPX4 activity (230)