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With this purpose, HUVECs were seeded into fibronectin-coated flexible silicone chambers to ensure optimal cell growth and adherence [220]

Tumor-associated fibrosis as a regulator of tumor immunity and response to immunotherapy

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To independently confirm this observation, we examined primary Atm / mouse embryonic fibroblasts (MEFs) and found that these constitutively null cells display a chronic accumulation of intracellular glutamate compared to controls (Fig