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Description

CRC Press, Boca Raton Holmes WM, Klaips CL, Serio TR (2014) Defining the limits: protein aggregation and toxicity in vivo

[DOI] [PubMed] [Google Scholar] Zheng D

17-Hydroxylase/17,20-lyase, an enzyme with two roles in steroidogenesis, is encoded by CYP17A1, which can convert progesterone into 17-hydroxyprogesterone and pregnenolone into 17-hydroxypregnenolone, and further catalyze these intermediates to dehydroepiandrosterone and androstenedione