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There was a B association between smokers whose OR was 0.81 with a 95% confidence interval between 0.73 and 0.90) and non-smokers whose OR was 0.97 and whose 95% confidence interval was between 0.93 and 1.02

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however, clinical translation remains limited by critical challenges: 1) Low bioavailability: The poor aqueous solubility of PPS limits gastrointestinal absorption, resulting in suboptimal systemic exposure and heterogeneous tissue distribution