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These animals were subjected to transcriptome and metabolome high-throughput sequencing to explore the molecular regulation of ovarian tissue in the context of differences in egg production

Mechanistically, POS downregulates genes involved in fatty acid and triglyceride synthesis, including ACC, FAS, SCD-1, and DGAT1, while upregulating lipolysis- and fatty acid oxidation-related genes such as ATGL, HSL, CPT1, and ACO, thereby suppressing lipogenesis and promoting lipid breakdown

10.1007/s12035-013-8496-5 122 WrightG

The epithelial cells of the gut are interconnected through intercellular junction complexes to form intestinal barriers, stabilizing the epithelial barriers integrity (114, 115)