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2.1.3.2 Preventing muscle loss and preserving insulin sensitivity Both Astragalus and yam have demonstrated protective effects against diabetes-related muscle wasting by modulating mitochondrial function through the Rab5a/mTOR signaling axis (35)

In summary, these findings support both the stimulation and inhibition of adipocyte lipolysis for therapeutic benefit, which will need to be specifically tailored to the disease state in question (Table 1)