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Issels, R

Key treatment strategies include antimicrobials, microbiota stabilization, anti-inflammation, antioxidation, angiogenesis, blood sugar regulation, O 2 /NO/H 2 supply, iron metabolism modulation, collagen deposition and scar prevention.Due to continuous attack exogenous pathogens, open wounds often display chronic inflammation

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Heme regulates B-cell differentiation, antibody class switch, and heme oxygenase-1 expression in B cells as a ligand of Bach2