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Measures in the first year of therapy predict the response to interferon beta in MS

acnes-induced inflammatory skin disease animal model

When endothelial cell functions are compromised, lipid and immune cells infiltrate the deeper layers of the vessel wall, triggering inflammation and free radical production

Considering that malignant cells need iron for proliferation and that TFR was demonstrated to be expressed on the surface of AML cells, it was tested if inhibition of the TFR may lead to an antiproliferative effect due to a decreased iron import