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Nature (2019) 575:68892

When to seek urgent medical advice: Call 999 or go to A&E for severe or uncontrolled bleeding, head injury while anticoagulated, or symptoms of stroke Use NHS 111 for urgent non-emergency advice about: Unusual bleeding or bruising Blood in urine or stools Prolonged bleeding from minor cuts Severe headaches or visual disturbances Unexplained INR fluctuations Any new symptoms after starting supplements NICE guidance on anticoagulation emphasises patient education and shared decision-making

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Kidney Int 98:14071418