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Such damage can be further exacerbated by neutrophil activation at the injury site

As it was recently suggested, GSH depletion could be the Trojan horse of COVID-19 severity and mortality and elevating GSH levels in tissues may decrease COVID-19 severity and mortality rates (Khanfar and Al Qaroot, 2020)

Notably, Fento-1 exhibited a residual toxicity that ferroptosis inhibitors could not fully overcome, which reflects the potency of Fento-1

Enhancements of caspase-3 and poly-(ADP-ribose) polymerase PARP levels and a reduction in the level of the Bcl2 protein in brain and liver tissues have been reported following exposure to D-galactose [5, 6, 40]