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FLAG-tagged BRD4 proteins were incubated with 500 ng of refolded RNA while rotating at 4 C for 1 h in RNA binding buffer (20 mM Tris-HCl at pH 7.4, 100 mM KCl, 0.2 mM EDTA, 0.05% NP40, 0.4 U RNase inhibitor, PICs)

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doi: 10.1046/j.1365-2249.2000.01218.x 141 SimRBMoestrupSKStuartGRLynchNJLuJSchwaebleWJet al

Advances in nanocarrier-based drug delivery systems, including polymeric nanoparticles, liposomes, and micelles, have shown promise in enhancing -SS stability, controlled release and targeted accumulation in inflamed synovial tissues