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The development of tumor treatment strategies targeting GSH-degrading enzymes faces challenges, including different roles of these enzymes in different types of tumor and their impact on the immune response or tumor microenvironment

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Our previous finding that pharmacological inhibition of extracellular HMGB1 attenuated NIHL supports the relevance of this pathway, yet how GSDMD is activated by acoustic overstimulation and contributes to HC loss is unknown 13

In: Ascorbic acid in plants, Springer briefs in plant science