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e-f , ALT and AST liver damage serum markers (n = 6 for Control, n = 9 for GGsTop) (e) and percent change in body weight (n = 10 per group) (f) in mice treated bi-daily with vehicle (saline) or 5 mg/kg i.p

Therefore, it plays a crucial role in immune function, detoxification capacity and protection against oxidative stress

Immunohistochemistry analysis indicated that chemotherapy-resistant patients had significantly higher expression levels of NRF2, GPX4 and SOD1 in tumor tissues compared to the sensitive ones

A patient may have a predominant acidic pH and clearance pattern with secondary mitochondrial stress, creatine demand or toxic burden