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David did. Meanwhile, in his lab, Sinclair pushed his studies up the evolutionary chain into mice, and in 2006 published the paper that would change his life: a study showing that overweight rodents fed resveratrol aged slower and stayed healthier than ones that did not consume the substance

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This disruption leads to blocked acetylcholine synthesis and secretion, resulting in cognitive impairments and affecting mood and memory in C57BL/6 mice (Wang L

The formalin test was also performed to differentiate its anti-nociceptive effect from an inflammatory reaction or central sensitization