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Apr 25 2023;120(17):e2211631120

232 Acetyl-L-carnitine is particularly important for nervous system function since it modulates neurotransmitter activity, increases activity of nerve growth factors, and appears to quiet pain signaling and inhibit pain sensitization

Decreased levels of TNF- and IL-6 indicate that NNMT inhibition not only modulates metabolism but also improves the inflammatory microenvironment, a key component in metabolic disease development and insulin resistance