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This suggests that the LD 50 for the methanol extract could be greater than 2,000 mg/kg in mice (722)

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2 Our international panel of experts in bone health, Chair Professor Richard Keen (Royal National Orthopaedic Hospital, UK), Professor Bente Langdahl (Aarhus University Hospital, Denmark), Professor Serge Ferrari (Geneva University Hospitals, Switzerland), and Professor Carmelinda Ruggiero (University of Perugia, Italy), will bring their invaluable insights and extensive real-world clinical experiences of adopting a romosozumab-first approach to proactively close the treatment gap in osteoporosis, which delegates can draw from to guide future clinical decision-making