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One of the key figures involved in this research was Claude Bernard (figure 2), a French physiologist based at the Medical School of Paris

The effects of St John's wort (Hypericum perforatum) on human cytochrome P450 activity

In a recent double-blind placebo-controlled RCT in 134 women undergoing caesarean section for pre-eclampsia, intravenous DEX (0.4 g/kg/min for 10 minutes before surgery) resulted in lower 2-microglobulin, kidney injury molecule-1, and urine protein, but not in significant differences in BUN, serum creatinine, or urine output