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PubMed, Moretti, Rita, et al

Neurology 66, S10S23

Using the MelaFulKutis 3D pigmented skin model under UV and methylglyoxal exposure, the DEC-containing serum also reduced melanin deposition and downregulated microphthalmia-associated transcription factor (MITF) and TYR expression by 63.37% and 80.39%, respectively

The significant increase in taurine, xanthine, and glutathione in tamoxifen-resistant cells indicates an increase in antioxidative activity in the cells, especially in the cell line under continuous tamoxifen treatment