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superoxide anion) play fundamental role in oxidative stress and oxidative damage in biological systems The primary role of oxidative stress (OS) in the etiology and progression of several disease conditions is evident by a number of clinical and experimental studies

Scorpio can exert an analgesic effect on rats with bone cancer pain by inhibiting bone destruction and suppressing the activation of spinal astrocytes and microglia (Yu et al., 2020).Since analgesia is the main pharmacological effect of Scorpio , in recent years, many scholars have been committed to isolating and purifying single-component analgesic active peptides from scorpion venom, the main active component of Scorpio