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[DOI] [PMC free article] [PubMed] [Google Scholar] 52.Alwine JC, Steinhart WL, Hill CW

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The research team reported that resveratrol (a sirtuin-1 activator) may be an effective agent for improving fatigue symptoms and arresting hippocampal atrophy by suppressing apoptosis and boosting neurogenesis

Nevertheless, challenging issues remain to be solved, such as poor encapsulation efficiency and the interference form exosomal endogenous nucleic acids and proteins