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In the study of curcumin-based non-competitive AMPAR antagonists, it was found that nitrogen affects the binding of receptors in the spillover loop, and both of which can reduce the activation current of AMPA [189]

EEG is an electrophysiological monitoring method to record electrical activity of the brain, measuring voltage fluctuations resulting from ionic current within the neurons of the brain [48]

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During this process, myofibroblasts irreversibly form, followed by the production of multiple types of collagens and accumulation of extracellular matrix, eventually resulting in renal tubulointerstitial fibrosis