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Thats because peptides can easily break down in the digestive tract and are often too molecularly large to permeate the intestinal wall.20 Oral alternatives may use technologies like protective capsules and permeability agents to bypass these obstacles, but injection remains the most common peptide delivery method.20 Collagen peptides are an exception

Statistical analysis Statistical analysis was performed using parametric two-way mixed model ANOVA (one factor is repeated-measures) and Student Newman-Keuls test to compare the difference between groups

DSIP has been investigated for possible modulatory effects on CRH signaling and downstream ACTH secretion

The latter mechanism seems less probable because inhibition of absorption was not observed with the stronger chelator D-penicillamine