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After 1 day, the cells were serum starved for 16 h and treated with 10 or 50 nM of human IGF1 (10011, PeproTech) for 5 min

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The SST extremes pattern has exhibited pronounced multidecadal variability consistent with the AMO, with a predominantly positive phase since the mid-1990s (Fig

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(4) Rapid pacing can induce myocardial degradation, decrease the LTCC, and increase the expression of p-RyR2 and TGF- [30]

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