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J Pharmacol Exp Ther 294(2):746752 Mager DE, Neuteboom B, Efthymiopoulos C, Munafo A, Jusko WJ (2003) Receptor-mediated pharmacokinetics and pharmacodynamics of interferon-beta1a in monkeys

Perhaps the most intriguing aspect of H2O2 biology is the recent report that antibodies have the capacity to convert molecular oxygen into hydrogen peroxide to contribute to the normal recognition and destruction processes of the immune system

These findings suggest that erastin does not react with any of the sulfhydryl group of cysteine residue in the xCT protein, although the possibility that erastin reacts with more than one cysteine residue to inhibit cystine uptake cannot be formally ruled out

doi: 10.1007/s10637-009-9302-0 87 JaganathanSKMandalM