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JACC Heart failure

TABLE 2 Evidence for pycnogenol effects categorized by study type and quality

This risk escalates with both prolonged periods of shift work and extended nighttime hours [37]

Second, they augment ROS clearance by supplying antioxidant moleculessuch as glutathione secreted by Saccharomyces boulardii (Badr et al., 2021)and by activating endogenous antioxidant systems