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Pharmacological targeting of glucose 6 phosphate dehydrogenase in human erythrocytes by Bay 117082, parthenolide and dimethyl fumarate Scientific Reports Glucose 6 Phosphate Dehydrogenase Deficiency and Cardiovascular Risk in Familial Hypercholesterolemia: A Retrospective Cohort Study In RBCs, NADPH are produced exclusively via HMP shunt by the action of G6PD and are responsible to maintain membrane integrity preventing premature destruction. That is why G6PD deficient RBCs are Glucose 6 phosphate Dehydrogenase (G6PD) Enzyme ROS Scavenger Biochemistry & Hematology YouTube

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