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Magnesium, commonly depleted by certain chemotherapy drugs, plays crucial roles in energy production, muscle function, and nerve transmission

Glutathione peroxidase 3 belongs to the conserved family of Glutathione Peroxidases and is the only member that is plasma-based, with the remainder of the 7 known GPx enzymes being localized intracellularly 30

Clinically, GABA and GABA analogs have been investigated as potential analgesics in CIPN and other conditions (Zarba et al., 2020) because GABAergic neurons and receptors are involved in coordination of the perception and response to noxious stimuli (Mullins et al., 2014) might help direct the development and optimization of non-invasive interventions to maximize GABAergic signaling through endogenous mechanisms

Gut microbiota mediates the protective effects of dietary capsaicin against chronic low-grade inflammation and associated obesity induced by high-fat diet