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The symptoms recorded throughout history include convulsions, sores, hallucinations or mania, headaches, nausea, gangrene, and burning extremities.[ref] Modern grain processing methods eliminate ergot as a problem in human food sources, but it can still affect animals that graze on grasses or contaminated grains.[ref] The neuroactive components in the ergot alkaloids are similar to precursor molecules for LSD

An imbalance between ROS production and elimination is termed oxidative stress, a critical factor and common denominator of many chronic diseases such as cancer, cardiovascular diseases, metabolic diseases, neurological disorders (Alzheimers and Parkinsons diseases), and other disorders

Oxidative stress and male infertility: from research bench to clinical practice

elegans causes a decrease in the expression of methylenetetrahydrofolate reductase (MTHF-1), methionine synthase (METR-1) and methionine synthase reductase (MTRR-1)