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Apolipoprotein E is a ligand for triggering receptor expressed on myeloid cells 2 (TREM2)

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Intriguingly, recent research has shown that lactate is not only essential for efferocytosis but also for sustaining efferocytosis-induced macrophage proliferation, a process responsible for increasing the number of macrophages capable of performing continuous efferocytosis, thus contributing to the resolution of inflammation and tissue repair [87] (Fig