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According to statistics published by the Centers for Disease Control and Prevention (CDC), 94% of patients who died with COVID 19 in 2020 had an average of 2.9 lifestyle-related comorbidities

In particular, increasing number of studies show that aberrant expression and activity of GRKs in the cardiovascular system and kidney inhibit or stimulate GPCRs (e.g., dopamine receptors, Ang II receptors, and - and -adrenergic receptors), resulting in hypertension