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Vrinda M Telang Debra M Beneck Harry S Dweck AbstractPediatric Research CARDIOVASCULAR RESPONSE TO ADENOSINE ANALOGS DIFFERS BETWEEN FETAL AND NEWBORN LAMBS Paul L Toubas Roder E Sheldon Thomas W Seale AbstractPediatric Research DIRECT MEASUREMENT OF HEME OXYGENASE ACTIVITY BY GAS CHROMATOGRAPHY Hendrik J Vreman David K Stevenson AbstractPediatric Research CHOLINERGIC MECHANISM IN THE CEREBRAL CIRCULATION OF THE NEWBORN PIGLET L Craig Wagerle David W Busija AbstractPediatric Research CEFTAZIDIME (CTZ) CLEARANCE (CL) WITH CONGENITAL URINARY TRACT OBSTRUCTION (UTO) Robert M Hard Mark F Bellinger Stan Davis AbstractPediatric Research THE NEED FOR A LOADING DOSE OF GENTAMICIN (G) IN NEONATES Kristi L Hatterberg H William Kelly AbstractPediatric Research DIGOXIN AND DIGITOXIN CLEARANCE IN THE HUMAN FETUS Carl P Welner Marietta I E Thompson AbstractPediatric Research NITRENDIPINE (N) TREATMENT OF HYPERTENSION: ACUTE AND LONG TERM EFFECTS IN CHILDREN Thomas G Wells Alan R Sinaiko AbstractPediatric Research CONGENITAL CONDITIONS ASSOCIATED WITH PERMANENT INFANTILE HYPOTHYROIDISM N E Congenital Hypothyroidism Collaborative AbstractPediatric Research PRELIMINARY REPORT ON PATIENTS WITH INFANTILE HYPOTHYROIDISM AFTER THE THIRD GRADE Ne Cong Hypothyroidism Collaborative AbstractPediatric Research QUANTITATION OF IMMUNOREACTIVE GH (IBGH) IN URINE Christine Albini Teresa Quattrin Margaret H Macgillivarey AbstractPediatric Research HIGH INCIDENCE OF PRENATAL AND PERINATAL MEDICAL COMPLICATIONS ASSOCIATED WITH GROWTH HORMONE NEUROSECRETORY DYSFUNCTION (GHND) Barry B Bercu Dorothy I Shulman Allen W Root AbstractPediatric Research DECREASED GROWTH HORMONE (GH) BINDING TO IM-9 CELLS IN CHILDREN WITH BIOLOGICALLY INACTIVE GH SYNDROME (BI) Tzvy Bistritzer Stuart A Chalew A Avlnoam Kowarski AbstractPediatric Research HUMAN GROWTH HORMONE VARIANT (hGH-B) PROMOTES GROWTH IN TRANSGENIC MICE Sandra L Blethen Richard F Selden Howard M Goodman AbstractPediatric Research ACROMEGALY PRESENTING IN INFANCY Denlse Blumberg Charles Sklar Raphael David AbstractPediatric Research DOSE-RELATED SUPPRESSION OF LH RESPONSE TO LHRH AND CLINICAL PARAMETERS BY NAFARELIN, AN INTRANASAL GnRH ANALOG R Brzyski C French F Comite AbstractPediatric Research HLA-DR PHENOTYPES IN CHILDREN WITH AUTOIMMUNE THYROIDITIS (AIT) Maria Buithieu William J Riley Noel K Maclaren AbstractPediatric Research INSULIN-LIKE GROWTH FACTOR-I (IGF-I) POTENTIATES LH-INDUCED STIMULATION OF ANDROGEN SYNTHESIS BY RAT OVARIAN THECA-INTERSTITIAL (TI) CELLS Jose F Cara Robert L Rosenfield AbstractPediatric Research HUMAN GROWTH HORMONE ADMINISTRATION INCREASES PLASMA OSTEOLCALCIN CONCENTRATIONS IN GROWTH HORMONE DEFICIENCY Salvador Castells Kenneth Rebong Sam Smith AbstractPediatric Research FAILURE OF CLONIDINE TO IMPROVE THE GROWTH HORMONE RESPONSE TO L-DOPA ADMINISTRATION Mariano Castro-Magaa Moris Angulo Amanda Sharp AbstractPediatric Research THE ROLE OF CARBOHYDRATE IN THE ASSOCIATION OF HCG SUBUNITS Christopher C Chang David C H Yang Hao Chia Chen AbstractPediatric Research EPIDERMAL GROWTH FACTOR ACUTELY REDUCES SOMATOMEDIN-C/1NSULIN-LIKE GROWTH FACTOR-I IN THE NEONATAL RAT S D Chernausek H T Hensgen S B Hoath AbstractPediatric Research GROWTH HORMONE (GH) DEFICIENCY ASSOCIATED WITH CRANIAL RADIATION IN ACUTE LYMPHOCYTIC LEUKEMIA (ALL) Gertrude Costin AbstractPediatric Research UNILATERAL MACRONODULAR ADRENAL HYPERPLASIA: A RARE CAUSE OF PRIMARY HYPERALDOSTERONISM Gertrude Costin Carl Grushkin AbstractPediatric Research GROWTH HORMONE SECRETORY PATTERNS IN NORMAL STATURED SUBJECTS Gertrude Costin Francine Kaufman Jo Anne Brasel AbstractPediatric Research SOMATOMEDIN-C/INSULIN-LIKE GROWTH FACTORS I (Sm-C/IGF-I) AND IGF-II mRNAs DURING LUNG DEVELOPMENT IN THE RAT Marsha L Davenport A Joseph D'Ercole P Kay Lund AbstractPediatric Research ABSENCE OF ULTRADIAN RHYTHM OR DIURNAL VARIATION IN CIRCULATING SOMATOMEDIN-C (Sm-C) IN RATS Kim C Donaghue Thomas M Badger William E Russell AbstractPediatric Research ADRENAL VEIN ALDOSTERONE LEVELS MAY DIFFERENTIATE ADENOMA FROM UNILATERAL HYPERPLASIA IN PRIMAEY HYPERALDOSTERONISM Margaret K Downey Maria I New AbstractPediatric Research ARGIMIME YASUPRESSIN (AP): A INDUCED ACTH SECRETION IN THE FETUS Daniel J Faucher John C Porter Charles R Rosenfeld AbstractPediatric Research ADAPTATION OF THE HYPOTHALAMIC-P ITU ITARY-ADRLNAL AXIS IN LATE-ONSET CONGENITAL ADRENAL HYPERPLASIA Penelope Feuillan Peter Avgerinos George Chrousos AbstractPediatric Research THE NON-HORMONAL ICDINE STATUS OF MOTHERS OF HYPOTHYROID INFANTS P Fort M Marks-Katz F Lifshitz AbstractPediatric Research ROLE OF GROWTH HORMONE ON PLASMA EPIDERMAL GROWTH FACTOR CONCENTRATIONS Joseph P Frindik Stephen F Kemp M Joycelyn Elders AbstractPediatric Research LEYDIG CELL TUMOR PRESENTING AS CONGENITAL ADRENAL HYPERPLASIA (CAH) Martin A Goldsmith Sharyn B Solish Walter L Miller AbstractPediatric Research COMPARISON OF HYPOTHALAMUS PITUITARY ADRENAL AXIS SUPPRESSION (HPAS) FROM TOPICAL STEROIDS BY STANDARD ENDOCRINE FUNCTION TESTING AND GAS CHROMATOGRAPHY MASS SPECTFOMETRY(GCMS) Ronald W Gotlin Paul V Fennessey W L Weston AbstractPediatric Research LIPOPROTEIN RESPONSE TO 5DIHYDROTESTOSTERONE(DHT) AND TESTOSTERONE(T) IN MACACA FASCICULARIS Nancy G Greger William Insull Bruce S Keenan AbstractPediatric Research AURENOLEUKUDYSTROPHY MAY RESEMBLE FAMILIAL ACTH UNRESPONSIVENESS Carol S Hart Stephen M Rosenthal Melvin M Grumbach AbstractPediatric Research ACTIVATION OF THE HYPOTHALAMIC-PITUITARY-GONADAL (HPG) AXIS IN PRETERM FEMALES Lynn A Hawkins Sandra L Blethen Fred I Chasalow AbstractPediatric Research SUPPRESSION OF GROWTH HORMONE AND THYROID HORMONE ASSOCIATED WITH VALPROIC ACID THERAPY Carol A Huseman Richard D Torkelson AbstractPediatric Research THE DIFFERENTIAL EXPRESSION OF INSULIN-LIKE GROWTH FACTOR mRNA IN TWO RAT TUMOR CELL LINES Philip M James M L Cleary R G Rosenfeld AbstractPediatric Research GLUCOCORTICOIDS REGULATE ADRENAL OPIATE PEPTIDES E F La Gamma J E Adler I B Black AbstractPediatric Research ONTOGENESIS OP HEPATIC EPIDERMAL GROWTH FACTOR (EGF) METABOLISM IN NORMAL BALB MICE Nilsa P Laborde Gertrudis G Buenaflor Delbert A Fisher AbstractPediatric Research PHARMACOKINETICS OF T 3 AND T 4 AFTER ACUTE THYRDXINE OVERDOSE: EFFECT OF PTU AND IOPANOCIC ACID Peter G Lacouture William J Lewander Frederick H Lovejoy AbstractPediatric Research BONE DENSITOMETRY IN CONGENITAL ADRENAL HYPERPLASIA (CAH) Mary M Lee Frances Ackland Thomas Moshang Jr

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Although anti-cancer therapy targeting metabolism has achieved some gratifying results, it is still currently believed that this field has the following shortcomings for possible future breakthroughs: 1) The side effects of such drugs limit their clinical effects as the optimal dose window is hard to be determined