glutathione reductase in caco-2 cells differentiated Apoptosis and glutathione: beyond an antioxidant Role of Glutathione in Cancer:

Among these were DNA damage-inducible transcript 3 (DDIT3), also known as CHOP, and tumor necrosis factor receptor superfamily member 10B (TSFRSF10B), also known as DR5, which have been implicated in apoptotic pathways triggered by the unfolded protein response in the endoplasmic reticulum (ER) (Lam et al., 2020)

^ Felig P., Pozefsk T., Marlis E., Cahill G.F

Recent clinical findings further support the translational relevance of these models, with MNPs now being detected in human atherosclerotic plaques and associated with increased cardiovascular risk

However, WADA prohibits substances with similar biological effects to those on the list, which creates gray areas