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In the non-parametric Mann Whitney U test, eight biomarkers showed a significant difference, in the DCM-induced animals displaying a significant increase in: TG (SMD 16.60, p = 0.0007), BG (SMD 7.54, p = 0.00001), TC (SMD 7.38, p = 0.009), EF% (SMD -4.13, p = 0.00001), NF-KB (SMD 3.13, p = 0.0001), HMGB1 (SMD 3.00, p = 0.0001), FS% (SMD -2.91, p = 0.00001) and HW/BW ratio (SMD 2.31, p = 0.007)

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Exposure to stress resulted in diminished hippocampal brain-derived neurotrophic factor (BDNF) expression in the CA3 region of neurons, a decrease in exploratory behavior, an increase in fecal output, and heightened levels of neuronal nitric-oxide synthase (nNOS), all of which are indicative of neural impairment (72)

Collagen peptides might benefit those looking to improve hair quality and thickness as part of a broader holistic treatment plan