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In summary, age-dependent changes such as increased catalytic iron levels, weakened antioxidant defenses, elevated mitochondrial-derived oxidative stress and sustained membrane vulnerability to peroxidation, collectively place neurons in the aging brain in a fragile state

Sept 14: After announcing Tuesday that its CRF1 antagonist, crinecerfont, met the primary efficacy endpoint in the Phase III CAHtalyst Adult Study for classic congenital adrenal hyperplasia, Neurocrine Biosciences reported good news on the neuro front

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