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Proc Natl Acad Sci USA 103:17681773 Sohal RS, Agarwal S, Candas M, Forster MJ, Lal H (1994) Effect of age and caloric restriction on DNA oxidative damage in different tissues of C57BL/6 mice

The presence of glutathione inside human cells does not prove that a particular externally supplied formulation reaches the target tissue, remains chemically stable or produces a clinically meaningful outcome