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These metrics offer a comprehensive evaluation of the models predictive power, focusing on both its ability to differentiate between outcomes and its overall accuracy while accounting for class imbalance

However, the levels of other metabolites such as 5-Aminolevulinate, cysteate, putrescine, 4-Aminobutyraldehyde, kynurenine, serotonin, Formyl-5-hydroxykynurenamine, 5-Hydroxykynurenine, 2-Aminomuconate, xanthine, and 5-Aminolevulinate were significantly increased in LC patients ( Figure 3C , Supplementary Figure 3A )

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Plasma glycine levels are reported to be approximately 300 M in [43]