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Research indicates Dihexa treatment can improve functional outcomes in animal models of cognitive impairment, with behavioral improvements correlating with structural brain changes including increased synaptic density and improved neural connectivity patterns

FY22 SBIR Program Summary Agency Dollars Obligated % Total DOD 2,145,738,302 52.134 % DOE 337,322,776 8.196 % NSF 202,553,284 4.921 % NASA 189,474,131 4.604 % USDA 34,738,810 0.844 % DHS 17,032,004 0.414 % DOC 14,398,941 0.350 % DOT 13,856,714 0.337 % ED 13,094,281 0.318 % EPA 7,290,965 0.177 % HHS 1,140,312,654 27.706 % Total $4,115,812,862 See more details at 2022 SBIR and STTR Annual Report on sbir.gov

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Then the animals received an intraperitoneal injection of saline (100 mL/kg) and were placed in individual cages for recovery