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, Xing Z., Li C., Wang J., and Wang Y

Tissue inflammation A histopathological analysis of the liver of rats exposed to aspartame at a dose of 240 mg/kg bw by intragastric intubation for 60 days showed severe hydropic degeneration of hepatocytes, which was characterized by swollen cells and clear fluids that replaced the cytoplasm, although nucleus, shape, and location were unaffected