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In some embodiments, the lipid nanoparticle may further include one or more helper lipids (also referred to herein as "co-lipids") including, but not limited to, neutral lipids, amphiphilic lipids, PEG-containing lipids, anionic lipids, and sterols

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DCs are essential antigen-presenting cells in the immune system, playing a vital role in activating T cells and initiating immune responses (154)