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The body has natural mechanisms to repair herniated discs: Spontaneous retraction of the herniated material back into the disc Reabsorption of water from the herniated portion, causing it to shrink Immune response that breaks down and removes disc fragments Several factors influence a discs ability to heal including age and overall health, severity and location of the herniation, and lifestyle factors such as exercise, posture, and aggravating activities

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The 80% increase in dentate gyrus neurogenesis and the reversal of dendritic and synaptic density loss make P21 particularly suited to the recovery phase, where the goal is not preventing further damage but restoring function