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Description

Molecular changes underlying reduced pineal melatonin levels in Alzheimer disease: alterations in preclinical and clinical stages

This in-turn compromised vitamin D regulatory genes

APRT, Adenine phosphorybosiltransferase

The top 20 transcription factors or chromatin regulators found in ChIP-seq experiments to bind to each gene was compiled, and the number of genes each factor bound to within the list of 61 was determined, with the top 9 regulators graphed, excluding the general factors EP300 and POL2RA